Most subjects in our clinical trial improved as early as 2 weeks, however it is possible for your acne to flare at the beginning of treatment. This is called a "purge." This can happen when acne-treating ingredients increase exfoliation and skin turnover. Don’t panic, this process is temporary, and should improve as you continue to regularly apply your products. Always best to consult your physician or healthcare provider if you are unsure or if you develop unwanted symptoms on your skin.